ARTICOLI SCIENTIFICI

Per maggiori informazioni consultate le seguenti pubblicazioni scientifiche.

1. Buono R, Longo VD. Starvation, Stress Resistance, and Cancer. Trends in endocrinology and metabolism: TEM. 2018;29(4):271-80. doi: 10.1016/j.tem.2018.01.008. PubMed PMID: 29463451.  PDF

2. Wei, M., et al., Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease. Sci Transl Med, 2017. 9(377).  PDF

3. Nashiro, K., et al., Brain Structure and Function Associated with Younger Adults in Growth Hormone Receptor-Deficient Humans. J Neurosci, 2017. 37(7): p. 1696-1707.  PDF

4. Lee, A.S., et al., Effects of Prolonged GRP78 Haploinsufficiency on Organ Homeostasis, Behavior, Cancer and Chemotoxic Resistance in Aged Mice. Sci Rep, 2017. 7: p. 40919.  PDF

5. Hine, C., et al., Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production. Cell Metab, 2017. 25(6): p. 1320-1333 e5.  PDF

6. Brandhorst, S., et al., Protective effects of short-term dietary restriction in surgical stress and chemotherapy. Ageing Res Rev, 2017.  PDF

7. Vernieri, C., et al., Targeting Cancer Metabolism: Dietary and Pharmacologic Interventions. Cancer Discov, 2016. 6(12): p. 1315-1333.  PDF

8. Song, M., et al., Association of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality. JAMA Intern Med, 2016. 176(10): p. 1453-1463.  PDF

9. Mattson, M.P., V.D. Longo, and M. Harvie, Impact of intermittent fasting on health and disease processes. Ageing Res Rev, 2016.  PDF

10. Dorff, T.B., et al., Safety and feasibility of fasting in combination with platinum-based chemotherapy. BMC Cancer, 2016. 16(1): p. 360.  PDF

11. Di Biase, S. and V.D. Longo, Fasting-induced differential stress sensitization in cancer treatment. Mol Cell Oncol, 2016. 3(3): p. e1117701.  PDF

12. Di Biase, S., et al., Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity. Cancer Cell, 2016. 30(1): p. 136-46.  PDF

13. Brandhorst, S. and V.D. Longo, Fasting and Caloric Restriction in Cancer Prevention and Treatment. Recent Results Cancer Res, 2016. 207: p. 241-66.  PDF

14. Shim, H.S., et al., Starvation promotes REV1 SUMOylation and p53-dependent sensitization of melanoma and breast cancer cells. Cancer Res, 2015. 75(6): p. 1056-67.  PDF

15. Hirschey, M.D., et al., Dysregulated metabolism contributes to oncogenesis. Semin Cancer Biol, 2015. 35 Suppl: p. S129-50.  PDF

16. Caffa, I., V.D. Longo, and A. Nencioni, Fasting plus tyrosine kinase inhibitors in cancer. Aging (Albany NY), 2015. 7(12): p. 1026-7. PDF

17. Block, K.I., et al., Designing a broad-spectrum integrative approach for cancer prevention and treatment. Semin Cancer Biol, 2015. 35 Suppl: p. S276-304. PDF

18. Mattson, M.P., et al., Meal frequency and timing in health and disease. Proc Natl Acad Sci U S A, 2014. 111(47): p. 16647-53. PDF

19. Longo, V.D. and M.P. Mattson, Fasting: molecular mechanisms and clinical applications. Cell Metab, 2014. 19(2): p. 181-92. PDF

20. Levine, M.E., et al., Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population. Cell Metab, 2014. 19(3): p. 407-17. PDF

21. Cheng, C.W., et al., Prolonged fasting reduces IGF-1/PKA to promote hematopoietic-stem-cell-based regeneration and reverse immunosuppression. Cell Stem Cell, 2014. 14(6): p. 810-23. PDF

22. Nencioni, A., et al., Autophagy in blood cancers: biological role and therapeutic implications. Haematologica, 2013. 98(9): p. 1335-43. PDF

23. Brandhorst, S., et al., Short-term calorie and protein restriction provide partial protection from chemotoxicity but do not delay glioma progression. Exp Gerontol, 2013. 48(10): p. 1120-8. PDF

24. Balasubramanian, P. and V.D. Longo, Aging, nutrient signaling, hematopoietic senescence, and cancer. Crit Rev Oncog, 2013. 18(6): p. 559-71. PDF

25. Safdie, F., et al., Fasting enhances the response of glioma to chemo- and radiotherapy. PLoS One, 2012. 7(9): p. e44603. PDF

26. Pfaffenbach, K.T., et al., GRP78/BiP is a novel downstream target of IGF-1 receptor mediated signaling. J Cell Physiol, 2012. 227(12): p. 3803-11. PDF

27. Lee, C., L. Raffaghello, and V.D. Longo, Starvation, detoxification, and multidrug resistance in cancer therapy. Drug Resist Updat, 2012. 15(1-2): p. 114-22. PDF

28. Fontana, L., M. Vinciguerra, and V.D. Longo, Growth factors, nutrient signaling, and cardiovascular aging. Circ Res, 2012. 110(8): p. 1139-50. PDF

29. Lee, C. and V.D. Longo, Fasting vs dietary restriction in cellular protection and cancer treatment: from model organisms to patients. Oncogene, 2011. 30(30): p. 3305-16. PDF

30. Longo, V.D. and L. Fontana, Calorie restriction and cancer prevention: metabolic and molecular mechanisms. Trends Pharmacol Sci, 2010. 31(2): p. 89-98. PDF

31. Lee, C., et al., Reduced levels of IGF-I mediate differential protection of normal and cancer cells in response to fasting and improve chemotherapeutic index. Cancer Res, 2010. 70(4): p. 1564-72. PDF

32. Blagosklonny, M.V., et al., Impact papers on aging in 2009. Aging (Albany NY), 2010. 2(3): p. 111-21. PDF

33. Safdie, F.M., et al., Fasting and cancer treatment in humans: A case series report. Aging (Albany NY), 2009. 1(12): p. 988-1007. PDF

34. Raffaghello, L., et al., Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy. Proc Natl Acad Sci U S A, 2008. 105(24): p. 8215-20. PDF

35. Madia, F., et al., Longevity mutation in SCH9 prevents recombination errors and premature genomic instability in a Werner/Bloom model system. J Cell Biol, 2008. 180(1): p. 67-81. PDF

36. Longo, V.D., M.R. Lieber, and J. Vijg, Turning anti-ageing genes against cancer. Nat Rev Mol Cell Biol, 2008. 9(11): p. 903-10. PDF

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