NEURODEGENERATIVE DISEASES

For further information, please refer to the following scientific papers.

CELL REPORTS/2022

Rangan, Priya et al. “Fasting-mimicking diet cycles reduce neuroinflammation to attenuate cognitive decline in Alzheimer’s models.” Cell reports vol. 40,13 (2022): 111417. doi:10.1016/j.celrep.2022.111417

THE JOURNAL OF NEUROSCIENCE / 2017
Behavioral/CognitiveBrain Structure and Function Associated with YoungerAdults in Growth Hormone Receptor-Deficient Human

CELL PRESS / 2016
A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple SclerosisSymptoms

CELL PRESS / 2016

AGING CELL / 2013
Protein restriction cycles reduce IGF-1 and phosphorylated Tau, and improve behavioral performance in an Alzheimer’s disease mouse model

AGING CELL / 2013

The Scientific World JOURNAL / 2010
Insulin/IGF-I and Related Signaling Pathways Regulate Aging in Non dividing Cells: from Yeast to the Mammalian Brain

NEUROENDOCRINOLOGY / 2009
Progesterone Influence on Neurite Outgrowth Involves Microglia

CELL PRESS / 2008
SirT1 Inhibition Reduces IGF-I/IRS-2/Ras/ERK1/2 Signaling and Protects Neurons

ELSEVIER / 2004
Progressive changes in regulation of apolipoproteins E and J in glial cultures during postnatal development and aging

ELSEVIER / 2004
Reversible age impairments in neurite outgrowth by manipulations of astrocytic GFAP

THE JOURNAL OF NEUROSCIENCE / 2002
Peroxynitrite Mediates Neurotoxicity of Amyloid-Peptide1–42- andLipopolysaccharide-Activated Microglia

ENDOCRINOLOGY / 2002
Estradiol (E2) Enhances Neurite Outgrowth byRepressing Glial Fibrillary Acidic Protein Expression and Reorganizing Laminin

AMERICAN MEDICAL ASSOCIATION / 2002
Genetics of Aging and Diseases

JOURNAL OF NEUROCHEMISTRY / 2000
Reversible Inactivation of Superoxide-Sensitive Aconitase inAb1–42-Treated Neuronal Cell Lines

EXPERIMENTAL NEUROLOGY / 1999
Variations of Synaptotagmin I, Synaptotagmin IV, and SynaptophysinmRNA Levels in Rat Hippocampus during the Estrous Cycle